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OPKO Health, Inc. (OPK) Stock

Healthcare · Medical - Diagnostics & Research · US
$1.71 0.00%
Last updated Nov 12, 2026 09:20 UTC

OPK Key Statistics

Market Cap$1.28B
P/E (TTM)-9.00
P/S (TTM)2.54
P/B (TTM)1.14
Revenue (TTM)$501.64M
EPS (TTM)$-0.19
Dividend Yield—
ROE (TTM)-12.41%
Net Margin-29.51%
Gross Margin56.56%
52W High$1.86
52W Low$0.98
Analyst ViewBuy
Price Target$3.13
Employees2,275
Volume2,648,091

About OPKO Health, Inc.

OPKO Health, Inc. operates as a healthcare enterprise with a dual focus on diagnostics and pharmaceuticals. Its operations span the United States, Ireland, Chile, Spain, Israel, Mexico, and other international markets. The company's Diagnostics division encompasses BioReference Laboratories, which delivers a comprehensive suite of laboratory testing services. These services are crucial for disease detection, diagnosis, evaluation, monitoring, and treatment, covering areas such as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare. BioReference serves a diverse client base, including medical practices, clinics, hospitals, employers, and government entities. Additionally, this segment provides a cutting-edge diagnostic instrument system designed for immediate, point-of-care blood test results, alongside its specialized 4Kscore testing for prostate cancer. Within the Pharmaceutical segment, OPKO offers a range of therapeutic products and a robust development pipeline. Key offerings include Rayaldee, indicated for the management of secondary hyperparathyroidism in adults suffering from stage 3 or 4 chronic kidney disease and vitamin D insufficiency. The pipeline features OPK88004, an investigational orally administered selective androgen receptor modulator; OPK88003, a peptide administered once weekly currently in Phase IIb trials for the treatment of type 2 diabetes and obesity; and hGH-CTP, a once-weekly human growth hormone injection that has successfully completed Phase III clinical trials in collaboration with Pfizer, Inc. A core strategy for this segment involves the development and commercialization of proprietary, extended-release versions of existing therapeutic proteins. Furthermore, OPKO Health supplies specialty active pharmaceutical ingredients (APIs) and is involved in the development, manufacturing, marketing, and sale of pharmaceutical, nutraceutical, veterinary, and ophthalmic products. The company also commercializes food supplements and over-the-counter products, produces and sells items primarily within the generics market, and handles the import, marketing, distribution, and sales of pharmaceutical products across various therapeutic areas, including cardiovascular conditions, vaccines, antibiotics, gastro-intestinal ailments, and hormone-related treatments, among others. Its pharmaceutical operations are further bolstered by platforms situated in Ireland, Chile, Spain, and Mexico. Founded in 1991, OPKO Health, Inc. maintains its corporate headquarters in Miami, Florida.

CEO: Phillip Frost. Company website

OPK — Frequently Asked Questions

What is the OPK stock price today?

OPKO Health, Inc. (OPK) trades at $1.71, up 0.00% on the day, as of Nov 12, 2026 09:20 UTC.

What is OPKO Health, Inc.'s market cap?

OPKO Health, Inc. has a market capitalisation of $1.28B, calculated from the live OPK share price and shares outstanding.

What is the P/E ratio of OPK?

OPK has no meaningful price-to-earnings ratio: OPKO Health, Inc. lost $0.19 per share over the last twelve months, and a P/E is only defined on positive earnings.

How much revenue does OPKO Health, Inc. make?

OPKO Health, Inc. generated revenue of $501.64M over the trailing twelve months, which puts the stock at 2.54 times sales.

What is the 52-week range for OPK?

OPK has traded between $0.98 and $1.86 over the past 52 weeks, and the last price is 8.1% below that high.

Is OPKO Health, Inc. profitable?

No. OPKO Health, Inc. is loss-making, with a net margin of -29.51% over the trailing twelve months.

What is the analyst price target for OPK?

Wall Street analysts rate OPK Buy, with an average price target of $3.13, 83.0% above the current price.

What sector is OPKO Health, Inc. in?

OPKO Health, Inc. is classified under the Healthcare sector and the Medical - Diagnostics & Research industry, and is domiciled in US.

Who is the CEO of OPKO Health, Inc.?

Phillip Frost is the chief executive of OPKO Health, Inc., which employs 2,275 people.

Where can I track OPK in real time?

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ETFs holding OPK

IBB iShares Biotechnology ETF 0.04% IWM iShares Russell 2000 ETF 0.02% SCHA Schwab U.S. Small-Cap ETF 0.02% SCHB Schwab U.S. Broad Market ETF 0.00% VTI Vanguard Morningstar Total Stock Market ETF 0.00%

Largest institutional holders of OPK

Rubric Capital Management LP 47,791,243 shares
BlackRock, Inc. BLK 36,978,893 shares
VANGUARD CAPITAL MANAGEMENT LLC 14,968,930 shares
VANGUARD PORTFOLIO MANAGEMENT LLC 14,934,924 shares
GEODE CAPITAL MANAGEMENT, LLC 11,050,263 shares
STATE STREET CORP STT 10,309,070 shares
GOLDMAN SACHS GROUP INC GS 7,035,492 shares
Whitefort Capital Management, LP 4,511,412 shares
NORTHERN TRUST CORP NTRS 3,756,163 shares
Sixth Street Partners Management Company, L.P. 3,596,980 shares

OPK insiders on other boards

DHR Danaher Corporation Zerhouni Elias A.