>_ QFI Terminal
Terminal › Stocks › ALNY

Alnylam Pharmaceuticals, Inc. (ALNY) Stock

Healthcare · Biotechnology · US
$159.85 +5.41%
Last updated Nov 12, 2026 09:32 UTC

ALNY Key Statistics

Market Cap$21.41B
P/E (TTM)8.07
P/S (TTM)4.27
P/B (TTM)5.94
Revenue (TTM)$5.01B
EPS (TTM)$19.80
Dividend Yield—
ROE (TTM)155.33%
Net Margin54.34%
Gross Margin77.28%
52W High$479.79
52W Low$149.18
Analyst ViewBuy
Price Target$330.54
Employees2,500
Volume3,359,218

About Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company primarily dedicated to the discovery, development, and commercialization of innovative therapeutic solutions leveraging ribonucleic acid interference (RNAi) technology. Its robust pipeline of RNAi-based treatments addresses a range of critical therapeutic areas, including inherited genetic disorders, cardio-metabolic conditions, hepatic infectious diseases, and central nervous system (CNS) and ocular disorders. Currently, Alnylam offers several approved therapies: ONPATTRO (patisiran) for adults suffering from polyneuropathy associated with hereditary transthyretin-mediated amyloidosis; GIVLAARI for adult patients with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for primary hyperoxaluria type 1 (PH1). Beyond its commercial portfolio, the company maintains an active development pipeline. Key investigational therapies include givosiran, aimed at adolescent patients with AHP; patisiran, being explored for transthyretin amyloidosis (ATTR) with cardiomyopathy; cemdisiran for complement-mediated disorders; ALN-AAT02 for AAT deficiency-associated liver disease; ALN-HBV02 for chronic hepatitis B virus infection; Zilebesiran for hypertension; and ALN-HSD for non-alcoholic steatohepatitis (NASH). Additionally, other candidates such as Fitusiran for hemophilia and bleeding disorders, Inclisiran for hypercholesterolemia, an expanded indication for lumasiran for advanced PH1 and recurrent kidney stones, and vutrisiran for ATTR amyloidosis (currently in Phase 3 clinical trials) are also progressing. Alnylam also engages in strategic alliances with other pharmaceutical leaders. Notable collaborations include those with Regeneron Pharmaceuticals, Inc., focused on discovering and developing RNAi therapeutics for ocular and CNS targets, and with Sanofi Genzyme for broader RNAi therapeutic development and commercialization efforts. Further licensing and partnership agreements are in place with entities such as Novartis AG, Vir Biotechnology, Inc., Dicerna Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., and PeptiDream, Inc. Established in 2002, Alnylam Pharmaceuticals maintains its corporate headquarters in Cambridge, Massachusetts.

CEO: Yvonne L. Greenstreet. Company website

ALNY — Frequently Asked Questions

What is the ALNY stock price today?

Alnylam Pharmaceuticals, Inc. (ALNY) trades at $159.85, up 5.41% on the day, as of Nov 12, 2026 09:32 UTC.

What is Alnylam Pharmaceuticals, Inc.'s market cap?

Alnylam Pharmaceuticals, Inc. has a market capitalisation of $21.41B, calculated from the live ALNY share price and shares outstanding.

What is the P/E ratio of ALNY?

ALNY trades at a trailing P/E of 8.07, from earnings per share of $19.80 over the last twelve months.

How much revenue does Alnylam Pharmaceuticals, Inc. make?

Alnylam Pharmaceuticals, Inc. generated revenue of $5.01B over the trailing twelve months, which puts the stock at 4.27 times sales.

What is the 52-week range for ALNY?

ALNY has traded between $149.18 and $479.79 over the past 52 weeks, and the last price is 66.7% below that high.

Is Alnylam Pharmaceuticals, Inc. profitable?

Yes. Alnylam Pharmaceuticals, Inc. keeps 54.34% of revenue as net income over the trailing twelve months.

What is the analyst price target for ALNY?

Wall Street analysts rate ALNY Buy, with an average price target of $330.54, 106.8% above the current price.

What sector is Alnylam Pharmaceuticals, Inc. in?

Alnylam Pharmaceuticals, Inc. is classified under the Healthcare sector and the Biotechnology industry, and is domiciled in US.

Who is the CEO of Alnylam Pharmaceuticals, Inc.?

Yvonne L. Greenstreet is the chief executive of Alnylam Pharmaceuticals, Inc., which employs 2,500 people.

Where can I track ALNY in real time?

QFI Terminal shows ALNY with live charts, full financials, the options chain with gamma exposure, institutional ownership and analyst ratings on one screen. The free plan has no time limit and asks for no card.

See ALNY live in QFI Terminal

Interactive charts, full financials, options chain, gamma exposure, ownership and analyst ratings, all in one institutional-grade terminal.

Open ALNY in Terminal See plans

Biotechnology stocks

REGN Regeneron Pharmaceuticals, Inc. VRTX Vertex Pharmaceuticals Incorporated ONC BeOne Medicines AG INCY Incyte Corporation JAZZ Jazz Pharmaceuticals plc ARGX argenx SE GMAB Genmab A/S NBIX Neurocrine Biosciences, Inc. BMRN BioMarin Pharmaceutical Inc. UTHR United Therapeutics Corporation CDT CDT Equity Inc. MRNA Moderna, Inc. EXEL Exelixis, Inc. BNTX BioNTech SE SRPT Sarepta Therapeutics, Inc. HALO Halozyme Therapeutics, Inc. INSM Insmed Incorporated MDGL Madrigal Pharmaceuticals, Inc. TECH Bio-Techne Corporation ASND Ascendis Pharma A/S CAI Caris Life Sciences, Inc. IONS Ionis Pharmaceuticals, Inc. BBIO BridgeBio Pharma, Inc. TGTX TG Therapeutics, Inc.

More Healthcare stocks

UNH UnitedHealth Group Incorporated CVS CVS Health Corp. MCK McKesson Corporation COR Cencora, Inc. NVO Novo Nordisk A/S CI Cigna Corporation CAH Cardinal Health, Inc. CNC Centene Corp. ELV Elevance Health Inc. HUM Humana Inc. JNJ Johnson & Johnson LLY Eli Lilly and Company HCA HCA Healthcare, Inc. MRK Merck & Co., Inc. ABBV AbbVie Inc. PFE Pfizer Inc.

ETFs holding ALNY

IBB iShares Biotechnology ETF 1.47% XBI State Street SPDR S&P Biotech ETF 0.88% USMV iShares MSCI USA Min Vol Factor ETF 0.35% VUG Vanguard Morningstar Growth ETF 0.11% QQQM Invesco NASDAQ 100 ETF 0.10% QQQ Invesco QQQ Trust, Series 1 0.10% SCHV Schwab U.S. Large-Cap Value ETF 0.07% IWF iShares Russell 1000 Growth ETF 0.07% TQQQ ProShares UltraPro QQQ 0.06% VTI Vanguard Morningstar Total Stock Market ETF 0.05% SCHX Schwab U.S. Large-Cap ETF 0.03% IWB iShares Russell 1000 ETF 0.03% SCHB Schwab U.S. Broad Market ETF 0.03% VT Vanguard Total World Stock ETF 0.03% ACWI iShares MSCI ACWI ETF 0.02%

Largest institutional holders of ALNY

FMR LLC 12,622,498 shares
Capital World Investors 11,144,846 shares
BlackRock, Inc. BLK 10,907,675 shares
Capital Research Global Investors 9,750,699 shares
VANGUARD PORTFOLIO MANAGEMENT LLC 6,538,390 shares
VANGUARD CAPITAL MANAGEMENT LLC 6,029,478 shares
T. Rowe Price Investment Management, Inc. 5,642,173 shares
BAILLIE GIFFORD & CO 5,492,469 shares
Invesco Ltd. IVZ 3,754,318 shares
STATE STREET CORP STT 3,555,689 shares

ALNY insiders on other boards

PCVX Vaxcyte, Inc. Brandicourt Olivier ONC BeOne Medicines AG Brandicourt Olivier MYGN Myriad Genetics, Inc. Reitan Colleen F ELV Elevance Health Inc. Schulman Amy W VRTX Vertex Pharmaceuticals Incorporated Arbuckle Stuart A