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BeOne Medicines AG (ONC) Stock

Healthcare · Biotechnology · CH
$419.98 -0.95%
Last updated Nov 12, 2026 09:31 UTC

ONC Key Statistics

Market Cap$44.88B
P/E (TTM)695.02
P/S (TTM)6.79
P/B (TTM)106.65
Revenue (TTM)$6.61B
EPS (TTM)$0.60
Dividend Yield—
ROE (TTM)18.21%
Net Margin13.86%
Gross Margin89.39%
52W High$424.73
52W Low$253.95
Analyst ViewBuy
Price Target$418.00
Employees12,000
Volume486,038

About BeOne Medicines AG

BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company’s commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton’s Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; SYLVANT for the treatment of adult patients with multicentric castleman disease; BAITUOWEI for patients with BC in premenopausal and perimenopausal women, and cancer; and PARTRUVIX for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK targeting chimeric degradation activation compound active against wild type and mutant BTK; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187 and BG-C0902, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. The company was formerly known as BeiGene, Ltd. and changed its name to BeOne Medicines AG in May 2025. BeOne Medicines AG was founded in 2010 and is based in Basel, Switzerland.

CEO: John V. Oyler. Company website

ONC — Frequently Asked Questions

What is the ONC stock price today?

BeOne Medicines AG (ONC) trades at $419.98, down 0.95% on the day, as of Nov 12, 2026 09:31 UTC.

What is BeOne Medicines AG's market cap?

BeOne Medicines AG has a market capitalisation of $44.88B, calculated from the live ONC share price and shares outstanding.

What is the P/E ratio of ONC?

ONC trades at a trailing P/E of 695.02, from earnings per share of $0.60 over the last twelve months.

How much revenue does BeOne Medicines AG make?

BeOne Medicines AG generated revenue of $6.61B over the trailing twelve months, which puts the stock at 6.79 times sales.

What is the 52-week range for ONC?

ONC has traded between $253.95 and $424.73 over the past 52 weeks, and the last price is 1.1% below that high.

Is BeOne Medicines AG profitable?

Yes. BeOne Medicines AG keeps 13.86% of revenue as net income over the trailing twelve months.

What is the analyst price target for ONC?

Wall Street analysts rate ONC Buy, with an average price target of $418.00, 0.5% below the current price.

What sector is BeOne Medicines AG in?

BeOne Medicines AG is classified under the Healthcare sector and the Biotechnology industry, and is domiciled in CH.

Who is the CEO of BeOne Medicines AG?

John V. Oyler is the chief executive of BeOne Medicines AG, which employs 12,000 people.

Where can I track ONC in real time?

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ETFs holding ONC

IBB iShares Biotechnology ETF 2.29%

Largest institutional holders of ONC

BAKER BROS. ADVISORS LP 8,801,567 shares
PRIMECAP MANAGEMENT CO/CA/ 5,007,931 shares
Capital International Investors 4,210,221 shares
FMR LLC 2,321,959 shares
Capital World Investors 2,249,582 shares
CITADEL ADVISORS LLC 1,425,517 shares
PRICE T ROWE ASSOCIATES INC /MD/ 758,752 shares
BlackRock, Inc. BLK 694,618 shares
MILLENNIUM MANAGEMENT LLC 543,323 shares
MORGAN STANLEY MS 497,437 shares

ONC insiders on other boards

MDGL Madrigal Pharmaceuticals, Inc. Baker Bros. Advisors Lp INCY Incyte Corporation Baker Bros. Advisors Lp REPL Replimune Group, Inc. Baker Bros. Advisors Lp PCVX Vaxcyte, Inc. Brandicourt Olivier RARE Ultragenyx Pharmaceutical Inc. Sanders Corazon (Corsee) D. OGN Organon & Co. Sharp Shalini DNLI Denali Therapeutics Inc. Baker Bros. Advisors Lp NBIX Neurocrine Biosciences, Inc. Sharp Shalini ALNY Alnylam Pharmaceuticals, Inc. Brandicourt Olivier