Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company dedicated to the discovery and advancement of genetic treatment modalities, including RNA-targeted therapeutics and gene therapies, specifically for rare diseases. The company currently offers two approved treatments: EXONDYS 51, prescribed for Duchenne muscular dystrophy (DMD) patients with confirmed dystrophin gene mutations amenable to exon 51 skipping, and VYONDYS 53, for DMD patients with exon 53 skipping mutations. Sarepta's development pipeline includes AMONDYS 45, an exon-skipping product candidate utilizing phosphorodiamidate morpholino oligomer chemistry for exon 45; SRP-5051, a peptide-conjugated PMO designed to target exon 51 of dystrophin pre-mRNA; and gene therapy programs such as SRP-9001 for DMD and SRP-9003 for limb-girdle muscular dystrophies. The company maintains collaborative agreements with organizations like F. Hoffman-La Roche Ltd, Nationwide Children's Hospital, Lysogene, Duke University, Genethon, and StrideBio. Founded in 1980, Sarepta Therapeutics is headquartered in Cambridge, Massachusetts.
CEO: Michael E. Severino. Company website
Sarepta Therapeutics, Inc. (SRPT) trades at $20.11, down 2.71% on the day, as of Sep 20, 2026 15:00 UTC.
Sarepta Therapeutics, Inc. has a market capitalisation of $2.12B, calculated from the live SRPT share price and shares outstanding.
SRPT has no meaningful price-to-earnings ratio: Sarepta Therapeutics, Inc. lost $2.90 per share over the last twelve months, and a P/E is only defined on positive earnings.
Sarepta Therapeutics, Inc. generated revenue of $1.97B over the trailing twelve months, which puts the stock at 1.08 times sales.
SRPT has traded between $14.68 and $25.32 over the past 52 weeks, and the last price is 20.6% below that high.
No. Sarepta Therapeutics, Inc. is loss-making, with a net margin of -6.93% over the trailing twelve months.
Wall Street analysts rate SRPT Buy, with an average price target of $23.33, 16.0% above the current price.
Sarepta Therapeutics, Inc. is classified under the Healthcare sector and the Biotechnology industry, and is domiciled in US.
Michael E. Severino is the chief executive of Sarepta Therapeutics, Inc., which employs 835 people.
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